ASSOCIATION BETWEEN EXPOSURE TO ENVIRONMENTAL RISKS AND ATOPIC DERMATITIS IN CHILDREN
DOI :
https://doi.org/10.17564/2316-3798.2025v10n1p646-659
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© Interfaces Científicas - Saúde e Ambiente 2026
Cette œuvre est sous licence Creative Commons Attribution - Pas d'Utilisation Commerciale 4.0 International.
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Résumé
Atopic dermatitis (AD) affects up to 20% of children and is influenced by genetic, immunological, and environmental factors. It is not fully known the impact of the environment on this dermatosis, the type of exposure to which children are closest, or which factors can cause or worsen the disease. The objective of this study is to evaluate the environmental exposures most associated with atopic dermatitis in children affected by the disease. To this, we have conducted a case-control study evaluated two groups of children matched for age, from 1 to 12 years old, through anamnesis focused on environmental aspects. Environmental factors were compared in the two groups looking for associations between environmental risks and atopic dermatitis. A total of 93 children were evaluated, 44 from the AD group and 49 from the control group. The 2 groups were similar in the main demographic variables. Children with AD live closer to gas stations (OR 9.7 - 95% CI 2.3-39.6; p = 0.02), have more visible mold inside the home (OR 7.2 - 95% CI 2.2-22.9; p <0.01.) and reported less pest control at home in the last 12 months. (OR 0.12 - 95% CI 0.02-0.58; p <0.01). There was no statistically significant difference regarding the proximity of factories, auto service centers, heavy traffic, planting with pesticides, open sewage, and waste recycling near the house. The study was not designed to assess the temporality and cause-effect relationship between risk factors and the main outcome, but it suggests associations between usually overlooked environmental variables and atopic dermatitis. The results showed that patients with atopic dermatitis live closer to gas stations, have more contact with mold and less frequent pest control at home.
